Hair Loss Blog
12/21/11
Hair Loss Blogs
Hair Loss Blog at MDST
Hair Loss Blog at blog.gohair/blog
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Hair Loss blog at hair-loss-treatment.com/b2
11/14/11
Treatment of Hair Loss in Chemotherapy
Dermatol Ther. 2011 Jul;24(4):432-42. doi: 10.1111/j.1529-8019.2011.01430.x.
Treatment of chemotherapy-induced alopecia.
Yeager CE, Olsen EA.
Source
Department of Dermatology, Duke University School of Medicine Duke Medical Center, South, Durham, North Carolina, USA.
Abstract
Chemotherapy-induced hair loss is well documented as a cause of distress to patients undergoing cancer treatment. Despite the importance of hair loss to patients, however, patients often receive little more counseling than the advice to purchase a wig or other head covering during their hair loss treatment. Research into non-camouflage (wigs, turbans, and head scarves) treatment methods has been complicated both by a lack of a standardized methodology for evaluating hair loss and hair regrowth and by a lack of human trials. Nevertheless, scalp cooling as a method of preventing hair loss during chemotherapy and 2% topical minoxidil as a therapy for accelerating regrowth after chemotherapy are both effective non-camouflage options for treatment. Other proposed treatments for prevention of hair loss during chemotherapy have demonstrated promise in early trials..... The increasing number of reports of permanent alopecia not just with pre-bone marrow transplant, high-dose busulfan, and cyclophosphamide regimens but also with standard breast cancer chemotherapy regimens illustrates the importance of further research into treatment methods for chemotherapy-induced hair loss.
Edited forhair loss blog use
09/20/11
Treatment of thinning eyelash hair
Clin Ophthalmol. 2010 Apr 26;4:349-58.
Bimatoprost in the treatment of eyelash hypotrichosis.
Law SK.
edited for hai rloss treatment blog
Eyelashes hypotrichosis is a condition indicated by an inadequate amount of eyelashes. Hypertrichosis of eyelashes, characterized by excessive eyelash hair loss, is a regular phenomenon associated with ophthalmic prostaglandin and prostamide analogs. Recently, the US Food and Drug Administration approved Latisse((R)) (bimatoprost 0.03% solution), identical to the ophthalmic solution for glaucoma treatment, for increasing eyelash length, thickness and darkness in patients with hypotrichosis of the eyelashes. When prostaglandin and prostamide analogs interact with the prostanoid receptors in the hair follicle, this most likely stimulates the resting follicles (telogen phase) to growing follicles anagen phase). Prostaglandin and prostamide analogs may also prolong the anagen phase of eyelashes, leading to an increase of eyelash length. Although bimatoprost is effective in promoting increased growth of healthy eyelashes and adnexal hairs, its effectiveness in patients with eyelash with hai rloss due to alopecia areata is debatable and its protective effect is not yet studied in patients with eyelash loss secondary to radiation or chemotherapy. Bimatoprost is generally safe when applied to the base of the eyelashes at the lid margin with minimum side effects. However, other ocular or systemic side effects associated with ophthalmic prostaglandin and prostamide analogs may occur when instilled on the sur face of the eye, and patients must be nformed and monitored.
hair loss treatment regrowth hair loss
09/06/10
Hair loss treatment
Hair loss treatment at the Proctor clinic.
Hair loss treatment and hair regrowth formulations.
08/23/10
Effect of tacrolimus in hair loss treatment
Clin Exp Dermatol. 2009 Dec;34(8):e937-40.
Topical tacrolimus suppresses the expression of vascular endothelial growth factor and insulin-like growth factor-1 in late anagen.
Wang Y, Yang S, Wu L, Tu P.
Department of Dermatology and Venerology, Peking University First Hospital, Beijing, China.
Abstract
Tacrolimus has shown promising results in the treatment of various dermatological diseases, including hair loss. The direct effect of tacrolimus on hair follicles and its underlying mechanisms have rarely been investigated. In this study, we investigated the effects of topical tacrolimus on anagen in the hair cycle and on the expression of vascular endothelial growth factor (VEGF) and insulin-like growth factor-1 (IGF-1) mRNAs in mouse skin. Topical tacrolimus 0.1% ointment was applied to one side of the skin of depilated C57BL/6 mice. Skin samples from both sides were taken during the study. Vegf and Igf-1 mRNA were determined by quantitative RT-PCR. No obvious difference in skin colour, hair cycling or histological features was found between the treated and untreated skin, but the levels of Vegf mRNA and Igf-1 mRNA were markedly decreased in the treated skin in late anagen, compared with those in untreated skin.
hair loss treatment and hair regrowth blog
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Hair Loss Treatment
- Capciacin effects on hair follicles
Neurosci Lett. 1987;74(2):139
Classification of aberrant primary afferents in the substantia gelatinosa of the rat following neonatal capsaicin treatment.
Beal JA, Knight DS.
Administration of capsaicin to newborn rats results in a loss of a large percentage of primary afferent C fibers many of which terminate in the substantia gelatinosa (SG). Using the Golgi silver impregnation technique, the present study shows that the loss of C fibers results in an invasion of aberrant myelinated primary afferents in the SG by 10 days after birth. The aberrant afferents, identified on the basis of their distinctive collateral arborizations, are derived from hair follicles and slowly adapting type I mechanoreceptors.
- Hair loss due to alopecia areata
J Invest Dermatol. 1985 Dec;85(6):569-72.Links
Expression of HLA-DR by anagen hair follicles in hair loss due to alopecia areata.Messenger AG, Bleehen SS.
The expression of HLA-DR within hair follicles in hair loss secondary to alopecia areata was studied using an immunoperoxidase method. Scalp biopsies were taken from 12 patients with hair loss due to alopecia areata and from 6 normal control subjects. Frozen sections were stained with a panel of 4 anti-HLA-DR monoclonal antibodies, Leu 2, Leu 3, Leu 4, and T6 antibodies. The expression of DR in normal hair follicles and in most anagen follicles from nonlesional alopecia skin was confined to dendritic cells which were sparse below the level of the arrector pilorum insertion. ..snip... The aberrant expression of DR antigens by hair follicle epithelium provides direct evidence that immune mechanisms are operating in the pathogenesis of alopecia areata- induced hair loss. In a previous study of alopecia areata we found evidence of cell injury confined to the precortical matrix and presumptive cortex in lesional anagen follicles. The relative restriction of epithelial DR expression to the same site suggests that this region of the follicle is of fundamental importance in the disease process.
- Hair Loss Treatment Blog
Hair Loss Treatment Blog
- Hormones in Hair loss in women
Int J Dermatol. 1992;31(12):858
Hormonal status in postmenopausal androgenetic alopecia.
Georgala S, et al
edited for blog
Androgenetic alopecia or pattern hair loss is thought to be caused by increased androgen action on hair follicles with menopause. Testosterone, estradiol and sex hormone binding globulin (SHBG) serum levels were determined in ten postmenopausal women with pattern hair loss and in ten sex and age matched healthy controls. No statistically significant differences were found in the hormone levels between the patients and the controls. These findings suggest that a genetically determined functional alteration of androgen receptors and/or a metabolic disturbance may exist in the hair follicle keratinocytes in pattern hair loss.
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